Authors

Abstract

The aim of present study was to assess the effects of resistance exercise on lipid peroxidation and DNA damage in competitive elderly wrestlers. 8 elderly wrestlers (age 59.75 ± 1.98, Height 172.25 ± 7.08, Weight 76 ± 14.6, body fat percentage 15.33 ± 5.07) and 7 untrained elderly men (age 61.42 ± 1.9, Height 173.14 ± 4.09, Weight 79.71 ± 8.15, body fat percentage 25.18 ± 0.98) volunteered as subject for the study. Subjects completed resistance exercise protocol including: leg press, bench press, leg extension,  lat-machine pull down, leg curl, cable triceps curl, cable biceps curl with 60-70% of 1RM and 8-12 repetitions. Blood samples were taken for measurement of lipid peroxidation (8-iso PGF2α) and DNA damage (8-OHdG) at pre, post and 24 hours after resistance exercise.  The independent t-test was used to assess the differences two groups and repeated measures ANOVA and Bonferroni post hoc test to determine differences between three blood samplings. After resistance exercise significance increase were observed in lipid peroxidation (p<0.05) and DNA damage (p<0.05) in both groups. In 24 hours after exercise the amount of indices significantly decreased and returned to basic levels. Untrained subjects had significantly more lipid peroxidation (p<0.05) and DNA damage (p<0.05) after resistance exercise. The results of this study showed that, long term and regular wrestling training can cause less oxidative damage in competitive trained elderly wrestlers than untrained elderly men after resistance exercise

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