Document Type : Research Paper
Authors
1 Associate Professor of Sport Physiology, Mohaghegh Ardabali University
2 Ph. D Student of Sport Physiology, Mohaghegh Ardabali University
3 M.Sc. of Sport Physiology, University of Tehran
Abstract
The purpose of this study was to determine the effect of eight weeks of aerobic training on lipid profile, glycosylated hemoglobin, fasting blood glucose, hs-CRP, insulin resistance and peptide hormone adiponectin in type 2 diabetic patients. For this purpose, twenty-two obese, sedentary females with type 2 diabetes (age 45.9±3.2 years and BMI=30.7±0.7 kg/m2, History of disease: 5.4±9.2 years and blood glucose 152.7±15.05 mg/dL), were selected and randomly divided into experimental (n=11) and control groups (n=11). The experimental group performed aerobic training for 8 weeks (three sessions per week, each session 60 minutes) with 60 to 80 percent of maximum heart rate. Blood samples were taken two days before and after 8 weeks of aerobic training. (HbA1c) by Electrochemiluminesence method, adiponectin, insulin and hs-CRP by ELISA, glucose, HDL-C, TG and LDL-C by direct methods and total cholesterol were measured by enzymatic methods. Homeostasis model assessment of insulin resistance by HOMA-IR was calculated. The results using the paired and independent t-test showed that, after the intervention, fasting blood glucose, insulin, insulin resistance, HbA1c, hs-CRP, cholesterol, triglycerides, LDL-C and weight, BMI, percent body fat significantly decreased and adiponectin levels significantly increased in the experimental group compared to the control. However, after 8 weeks of aerobic exercise HDL-C increased in the experimental group, but HDL-C levels difference was not significant between the two groups. A significant inverse correlation between serum adiponectin levels with glucose, total cholesterol, triglycerides, body weight and body fat percentage and no significant correlation with HDL was observed. According to the findings of the present study was the reduction in visceral fat and lipid levels by eight weeks of aerobic exercise may the performance of adiponectin and reduce insulin resistance in diabetic patients is effective.
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Main Subjects
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