The Effect of 12 Weeks Continuous Training at Fatmax Intensity or Anaerobic Threshold, and High Intensity Interval Training on Fat Burning Capacity in Pre-Diabetic Patients

Document Type : Research Paper

Authors

1 Professor of Sport Physiology, University of Guilan, Iran

2 Ph.D. in Sport Physiology, University of Guilan, Iran

3 Assistant Professor of Sport Physiology, Sport Sciences Research Institute of Iran, Tehran, Iran

Abstract

Fat metabolism disorders is a defect in pre-diabetic patients and a basis for type 2 diabetes. The aim of this study was to investigate the effect of 12 weeks continuous or high intensity interval training on fat burning capacity in pre-diabetic patients. 32 pre-diabetic patients (age: 38.7 ± 4.0 years; BMI: 26.9 ± 1.4 kg/m2; percent body fat: 26.1 ± 2.5%; VO2Peak: 2.49 ± 0.22 L.min-1) were divided into four groups: control (CON), high intensity interval training (HIT), continuous training at Fatmax intensity (FAT) and continuous training at anaerobic threshold (IAT). HIT, FAT and IAT groups participated in a 12-weeks training program with 4 sessions per week (with intensity of 90% VO2peak during the intervals, Fatmax intensity and/or anaerobic threshold intensity, respectively). Substrate oxidation, maximal fat oxidation (MFO) and Fatmax were determined during graded exercise test using the stoichiometric equations. Student’s t-test and ANOVA were used to analyze the data. MFO was affected by training in HIT, FAT and IAT groups by 26%, 35% and 25%, respectively, which it was significantly different between FAT group and HIT and IAT groups (P ≤ 0.05). In addition, the effect of exercise training on Fatmax in HIT, FAT and IAT groups was 26%, 25% and 35%, respectively, which it was significantly different between FAT and IAT groups (P ≤ 0.05). Results showed that changes in fat oxidation rate was different in three groups compared to pre-training status. This means that the intensity and type of exercise may have effective role in fat oxidation metabolism in pre-diabetic patients.

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Main Subjects

References

  1. Tabak AG, Herder C, Rathmann W, Brunner EJ, Kivimaki M. Pre diabetes: A high-risk state for diabetes development. Lancet. 2012;379:2279–90.
  2. Earnest CP. Exercise interval training: An improved stimulus for improving the physiology of pre-diabetes. Med Hypotheses. 2008;71:752-61.
  3. Kevin R, April M, David A, Steven D. Lower resting energy expenditure and fat oxidation in native American and Hispanic infants born to mothers with diabetes. J Pediatr. 2015;166:884–9.
  4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2011;34:62–9.
  5. Li G, Zhang P, Wang J. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing diabetes prevention study: A 20-year follow-up study. Lancet. 2008;371:1783–9.
  6. Mohebbi H, Nourshahi M, Ghasemikaram M, Safarimosavi S. Effects of exercise at individual anaerobic threshold and maximal fat oxidation intensities on plasma levels of nesfatin-1 and metabolic health biomarkers. J Physiol Biochem. 2015;71:79-88.
  7. Achten J, Venables MC, Jeukendrup AE. Fat oxidation rates are higher during running compared with cycling over a wide range of intensities. Metabolism. 2003;52:747–52.
  8. Venables M, Jeukendrup A. Endurance training and obesity: Effect on substrate metabolism and insulin sensitivity. Med Sci Sports Exer. 2008;40:495–502.
  9. Ben Ounis O, Elloumi M, Amri M, Zbidi A, Tabka, Z, Lac G. Impact of diet, exercise and diet combined with exercise programs on plasma lipoprotein and adiponectin levels in obese girls. J Sport Sci and Med. 2008;7:437-45.
  10. Bruce CR, Hawley JA. Improvements in insulin resistance with aerobic exercise training: A lipocentric approach. Med Sci Sports Exer. 2004;36:1196–201.
  11. Oliveira BR, Slama FA, Deslandes AC, Furtado ES, Santos TM. Continuous and high-intensity interval training: which promotes higher pleasure? PLoS One. 2013;268(11):79965.
  12. Snowling NJ, Hopkins WG. Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients: a meta-analysis. Diabetes Care. 2006;29:2518–27.
  13. Janatan JP, Gillen JB, Percival ME, Safdar A, Tarnopolsky MA, Punthakee Z, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J Appl Physiol. 2011;111:1554-60.
  14. Riddell MC, Jamnik VK, Iscoe KE, Timmons BW, and Gledhill N. Fat oxidation rate and the exercise intensity that elicits maximal fat oxidation decreases with pubertal status in young male subjects. J Appl Physiol. 2008;105:742–8.
  15. Jeukendrup AE and Wallis GA. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med. 2005;26:28–37.
  16. Martin JG, Jonathan PL, Maureen JM, John AH. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol. 2012; 590(5):1077–84.
  17. Van Aggel-Leijssen D, Saris W, Wagenmakers A, Senden J, Van Baak M. Effect of exercise training at different intensities on fat metabolism of obese men. J Appl Physiol. 2002;92:1300-9
  18. Alkahtani SA, King NA, Hills AP, Byrne NM. Effect of interval training intensity on fat oxidation, blood lactate and the rate of perceived exertion in obese men. Springer Plus. 2013;2:532-2.
  19. Talanian J, Galloway S, Heigenhauser G, Bonen A, Spriet L. Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women. J Appl Physiol. 2007;102:1439–47.
  20. Wang L, Psilander N, Tonkonogi M, Ding S, Sahlin K. Similar expression of oxidative genes after interval and continuous exercise. Med Sci Sports Exer. 2009;41:2136–44.
  21. Laursen P. Training for intense exercise performance: high-intensity or high-volume training? Scandinavian J Med Sci Sports. 2010;20:1–10.
  22. Rohani H, Safarimosavi SS, Gholamian S, Farzaneh S. Comparison the maximal fat oxidation and Fatmax in trained and untrained women. Exer Physiol. 2015;28:31-44. (In Persian).  
  23. Safari Mosavi SS, Mohebbi H, Damirchi A, Hovanlo F. Effect of reduced muscle glycogen on MFO and Fatmax during exercise in untrained men. J Metab Exer. 2013;2:113-23. (In Persian).  
  24. Stisen AB, Stougaard O, Langfort J, Helge JW, Sahlin K, Madsen K. Maximal fat oxidation rates in endurance trained and untrained women. Eur J Appl Physiol. 2006;98:497-506.
  25. Adriano EL, Romulo CB, Flavio OP, Joao FG, Ronaldo V, Barros JH, et al. Relationship between training status and maximal fat oxidation rate. J Sports Sci and Med. 2010;9:31-5.
  26. Astorino TA, Schubert MM, Palumbo E, Stirling D, Mcmillan D. Effect of two doses of interval training on maximal fat oxidation in sedentary women. Med Sci Sports Exerc. 2013;45:1878–86.
  27. Tremblay A, Simoneau JA, Bouchard C. Impact of exercise intensity on body fatness and skeletal muscle metabolism. Metabolism. 1994;43:814–8.
Sport Physiology
Volume 11, Issue 41
April 2019
Pages 31-46

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History

  • Receive Date: 25 February 2017
  • Revise Date: 01 July 2017
  • Accept Date: 23 July 2017

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