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The Effect of Rapid Weight Loss on the Levels of Wrestler’s Brain Neurometabolites Using the Proton Magnetic Resonance Spectroscopy

Document Type : Research Paper

Authors

1 Ph.D. in Sport Physiology, University of Mazandaran

2 Associate Professor of Sport Physiology, University of Mazandaran

Abstract

The purpose of this study was to investigate the effect of rapid weight loss on the levels of N-acetyl aspartate and myo-inozitol of the wrestlers using the proton magnetic resonance spectroscopy method. For this purpose, 21 wrestlers were selected. Of these, 11 wrestlers (21.28 ± 2.14 years old, 72.47 ± 4.38 kg, BMI = 23.66 ± 1.34 kg / m2, VO2max = 55.81±2.22 ml / kg / min) according to the criteria for entering the research as an experimental group and 10 subjects (age = 22.27 ± 2.55 years, weight = 69.02 ± 4.30kg, BMI=22. 67±.73 kg / m2, VO2max = 55.50 ± 1.90 ml / kg / min) were also selected as control group. After assessing the body composition and aerobic fitness levels, brain metabolites (MI / Cr, NAA / Cr) were evaluated by HMRS method in both experimental and control groups. Rapid weight loss in the experimental group for 3 days and with the use of extreme food restriction and acute dehydration methods was carried out. The results showed that the mean change in NAA / Cr levels in the experimental group compared to control in the post test had a non-significant reduction (P = 0.146). Mean changes in MI / Cr levels showed a significant increase in the experimental group compared to the control group in posttest (P = 0.001). The results of the study showed that rapid weight loss in wrestlers could disrupt the levels of metabolites associated with brain function, which in part could be indicative of reduced nerve and mitochondrial function and disorder of osmolality and neuronal volume.

Keywords

Main Subjects

References
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Sport Physiology
Volume 10, Issue 40
Winter 2019
January 2019
Pages 133-148
Files
History
  • Receive Date: 07 January 2019
  • Revise Date: 26 April 2019
  • Accept Date: 08 May 2019
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