Document Type : Research Paper
Authors
1 M.Sc. in Excersice Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2 Assistant Professor of Biochemistry, Shahid Chamran University of Ahvaz
3 Associate Professor of Excersice Physiology, Shahid Chamran University of Ahvaz
Abstract
The aim of this study was to evaluate the effect of six weeks of continuous and periodic aerobic exercise on total antioxidant index of hippocampus and balance in rats with Parkinson's disease. Twenty-four Wistar male rats (250-350 gr) were used in this study. Subjects were infected with reserpine to Parkinson's. Then, continuous and periodic aerobic exercises were performed for 6 weeks and 5 sessions per week with a time of 15 minutes and a speed of 10 meters per minute in the first week, the training time in the last week reached 40 minutes and the training speed reached 20 meters per minute. This exercise was performed in the periodic group in the first week in two stages, in the second to fourth week in four stages, and in the fifth and sixth weeks in six stages. They were killed by ketamine and xylazine, then the hippocampal tissue was isolated from other parts of the brain and the total antioxidant index (TAC) was measured. The results were analyzed using one-way analysis of variance and LSD post hoc test. The results of this study showed that 6 weeks of continuous and interval aerobic exercise improved the total antioxidant index (P≤0.00), and the balance (P≤0.00) of parkinsons rat. Also, there was no significant difference between the two training groups in the total antioxidant index (P≤0.46), but in the interval exercise equilibrium index, there was a significant difference between the two exercises (P≤0.00),Therefore, it can be concluded that these types of exercises can be used to Improve the hippocampal antioxidant system and balance of Parkinson's patients.
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Main Subjects
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