Effect of Low Intensity Endurance Training and High Intensity Interval Training on HIG2 Gene Expression and Visceral Adipose Tissue Triglyceride Content in Rats with NAFLD

Document Type : Research Paper

Authors

1 Ph.D. Student of Exercise Physiology, Department of Sport Sciences, Shahrekord University, Shahrekord, Iran

2 Associate Professor of Exercise Physiology, Department of Sport Sciences, Shahrekord University, Shahrekord, Iran

3 Associate Professor in Clinical Biochemistry, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

The main purpose of this study was to compare the effect of an eight-week LIET and HIIT, on the amount of HIG2 gene and TG content of visceral lipid tissue in wistar male rats affected by NAFLD. The present research was performed on 40 wistar rats affected by NAFLD. The rats were divided into four-ten groups Healthy Control (Standard Diet), control, LIET and HIIT (High fat diet). After 16-weeks of using special diet and end of practical or training period. HIIT training protocol consisted 90% and The LIET training protocol composed of running with 45% maximum speed intensity. HIG2 gene expression by real-time PCR technique and TG measurements visceral lipid tissue was done by auto analyzer (BT3000 model). Analysis of data revealed that there is no significant difference in HIG2 gene expression among training groups compared to control groups (p=0.05). The increasing significance was observed in HIG2 gene expression amount merely in control group (p=0/039) compared to experimental group. There was a significant deference in the amount of TG content between control group and LIET group (p=0/001) and between control group and HIIT group (p=0/001) and between LIET and HIIT group (p= 0/003). It can be concluded that considerable continuation of fatty diet during the training and the influence of exercises on the amount of TG; and on effect on HIG2 gene expression demonstrate that each of the tow training program, independent of HIG2 gene, had an effect on visceral fat content in NAFLD affected rats.

Keywords

Main Subjects

References

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Sport Physiology
Volume 13, Issue 50 - Serial Number 50
September 2021
Pages 87-110

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History

  • Receive Date: 14 November 2018
  • Revise Date: 12 March 2019
  • Accept Date: 16 March 2019

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