Document Type : Research Paper

Authors

Abstract

This study aimed to identify the possible effects of the different types of exercise on levels of brain-derived neurotrophic factor (BDNF-Brain-Derived Neurotrophic Factor) in the hippocampus of adult rats. In this experimental-trail, Thirty-five Wistar rats were divided into five groups: (1) Sedentary (Sed), (2) Endurance Training (ET), (3) High-Intensity Interval Training (HIIT), Sprint Training (ST), Incline Treadmill Workout (ITW); Sed group was regarded as control. ET group received 8-wk Mild-intensity endurance exercise. The exercise schedule of HIIT group consisted of high intensity interval training for 8 weeks (with Active recovery). ST group ran on treadmill for 8-weeks with high intensity. ITW group ran on the inclined treadmill. Hippocampal BDNF protein was assessed using commercial ELISA kits and the data were analyzed by one-way ANOVA. Statistical differences were considered significant at α<0.05. The results showed that all training groups had no significant differ in BDNF protein level comparison with the Sd group (PET=0.786, PHIIT= 0.135, PST= 0.163, PITW=0.172). However, altered exercise training did not differ significantly BDNF levels, it seems, higher intensity exercise and stress can affect more change in hippocampus BDNF levels.
 

Keywords

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