Document Type : Research Paper
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Abstract
The aim of the present study was to evaluate the influence of vitamin E supplementation on selective testes oxidative stress markers and spermatogenesis during 8 weeks of intensive training in male rats. A total of 30 male rats (age: 3 months, weight: 247±10g) were randomly assigned to Control (C, n=10), intensive exercise (IE, n=10) and intensive exercise + supplement (IE+S) groups. The intense exercise protocol consisted of 5 days per week of training for 8 weeks. In IE+S group, vitamin E was injected at a dose of 50 mg/kg/day. All the animals were killed and testes were collected for evaluation of different parameters. Data were analyzed using SPSS-15 and ANOVA test. A significant elevation in malon di aldehyde (MDA) levels (P<0.02) along with significant reduction in spermatogenesis quality (P<0.03) were observed in testes of IE group. In the IE+S group, testes total antioxidants capacity (FRAP) significantly increased (P<0.03), whereas MDA levels and spermatogenesis quality remained unchanged (P>0.05). These results suggest that the vitamin E supplementation may be effective in protecting the probable aggravating effects of intensive exercise on spermatogenesis and fertility capacity
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