Document Type : Research Paper
Authors
1 Master's degree, Sports Physiology Department, Faculty of Sports Sciences, Gilan of University, Rasht, Iran.
2 exercise physiology, faculty of physical education and sport sciences, University of Guilan, Rasht, IRAN
3 Professor, Department of Neurology, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Abstract
Multiple Sclerosis (MS) is a chronic, progressive, immune-mediated disorder that affects the Central Nervous System and is the most common cause of non-traumatic neurological disability in young adults. The purpose of this study was to investigate the effect of eight weeks of home resistance training on serotonin, melatonin, sleep quality and quality of life in women with MS. 26 female patients with relapsing-remitting MS with an EDSS score between 0 and 5.5 who referred to the neurology clinic of Rasht University of Medical Sciences were divided into two resistance training groups and a control group. The resistance training program was eight weeks of exercise at home, this periodization technique included 4 weeks of hypertrophy phase and 4 weeks of strength phase. Sleep quality was evaluated through the sleep quality questionnaire and the 26-question quality of life questionnaire of the World Health Organization. Also, serum melatonin and serotonin levels before and after the training period were evaluated using an ELISA kit. The data of the study was analyzed at the level of 0.05 using the statistical method of covariance. Studies show that the levels of melatonin, serotonin, quality of life and sleep quality did not change significantly during eight weeks of resistance training (P<0.05). These results showed that resistance training does not improve melatonin levels or sleep quality in MS patients. It seems that the implementation of exercises without direct supervision will lack the effect of the audience and the necessary motivation for their effectiveness.
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