Introduction: Several studies have investigated the effect of curcumin supplementation on muscle damage factors and muscle soreness after exercise in athletes. However, the results of some studies indicate that curcumin supplementation does not have many benefits on muscle soreness after exercise. The aim of the present study was to investigate the effect of curcumin supplementation on muscle damage factors and muscle soreness after exercise in adults. Materials and methods: A systematic search of published articles from English and Persian databases until March 2024 was conducted to investigate the effect of curcumin supplementation on muscle sureness and muscle damage factors (serum creatine kinase CK, lactate dehydrogenase LDH and myoglobin MB) and range of motion in adults. Weighted mean difference (WMD) and standardized mean difference (SMD) and 95% confidence interval were calculated using random effect model. Results: A total of 23 studies including 564 subjects were included in the present meta-analysis. . The results of the main analysis showed that curcumin supplementation caused a significant reduction in muscle sureness [WMD=-0.86 (-1.08 to 0.64), P=0.001], serum CK [SMD=-0.58 ng/ml (-0.84 to -0.33), P=0.001], LDH [SMD=-0.65 (-1.02 to -0.28), P=0.001], and myoglobin [WMD=-14.36 ng/ml (-25.04 to -3.67), P=0.008] was compared to the control group for all measured times after exercise. Also, curcumin caused a significant increase in ROM [SMD=0.67 (0.14 to 1.21), P=0.01] in 72 hours after exercise, compared to the control group. Conclusion: The results of the present meta-analysis study show that curcumin supplementation reduces muscle sureness and muscle damage factors after exercise.
Kazeminasab, F. and Ahmadi nejad, S. (2024). The effect of curcumin supplementation on muscle damage factors and muscle sureness after exercise in adults: a systematic review and meta-analysis. Sport Physiology, 16(63), -. doi: 10.22089/spj.2025.16975.2321
MLA
Kazeminasab, F. , and Ahmadi nejad, S. . "The effect of curcumin supplementation on muscle damage factors and muscle sureness after exercise in adults: a systematic review and meta-analysis", Sport Physiology, 16, 63, 2024, -. doi: 10.22089/spj.2025.16975.2321
HARVARD
Kazeminasab, F., Ahmadi nejad, S. (2024). 'The effect of curcumin supplementation on muscle damage factors and muscle sureness after exercise in adults: a systematic review and meta-analysis', Sport Physiology, 16(63), pp. -. doi: 10.22089/spj.2025.16975.2321
CHICAGO
F. Kazeminasab and S. Ahmadi nejad, "The effect of curcumin supplementation on muscle damage factors and muscle sureness after exercise in adults: a systematic review and meta-analysis," Sport Physiology, 16 63 (2024): -, doi: 10.22089/spj.2025.16975.2321
VANCOUVER
Kazeminasab, F., Ahmadi nejad, S. The effect of curcumin supplementation on muscle damage factors and muscle sureness after exercise in adults: a systematic review and meta-analysis. Sport Physiology, 2024; 16(63): -. doi: 10.22089/spj.2025.16975.2321
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