Document Type : Research Paper

Authors

Abstract

The purpose of this study was to investigate the effect of sequence order of combined training (strength and endurance) on myostatin, follistatin and follistatin/myostatin ratio in older women. 40 healthy elderly women (age: 60.34±0.82 years, height: 155±0.01 cm, weight:71.72±1.89 kg And BMI: 29.45±0.63 kg/m2) were randomly placed into four groups, strength + endurance (S+E) (n=10), endurance + strength (E+S) (n=9), alternative concurrent training (ACT) (n=12) and control (n=9) groups. The training program was done eight weeks, 3 times per week. Endurance training performed on a cycle ergometer (intensity: 60-80 % MHR) and strength training involved several upper and lower body workout (intensy: 40-75 1RM, 8-18 repeat). The results showed that myostatin and follistatin serum concentrations not significantly changed (P≥0.05) following three different orders. The follistatin/myostatin ratio increased in E+S group, but this increase was not significant (P≥0.05). There was a significant decrease in follistatin/myostatin ratio following S+E training. (P=0.04). Furthermore, there were significant increases in upper-body strength in E+S (P=0.005) and ACT (P=0.02) groups and increase in lower-body strength in all groups (P≤0.05). According to results of this study, order of combined training could influence functional adaptation induce by exercise training. Also, it appears the sequences of endurance+strength concurrent training cause a more anabolic status and the sequences of strength+endurance training cause a more catabolic status.

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