Objectives: The aim of this study was to investigate the effect of 10 weeks of aerobic-resistance and aerobic-resistance training on C-reactive protein, homocysteine, insulin resistance, and lipid profile in obese women with type 2 diabetes.
Materials and Methods: The present study was conducted in a quasi-experimental manner by voluntarily selecting 36 women aged 40 to 60 years in Bojnourd. These individuals were divided into 3 groups of 12 individuals: control (not doing sports) and two experimental groups that performed aerobic exercises before and after resistance exercises by simple randomization. Blood samples were taken before exercise and 48 hours after exercise (12 hours fasting), and biochemical parameters were measured with kits, and then the data were analyzed by analysis of variance and Fisher's exact test at p≥0.05 level.
Results: This study showed a significant difference between hemoglobin A1C, homocysteine, C-reactive protein, and insulin resistance before and after aerobic-resistance training. Ten weeks of combined resistance-aerobic training had a significant effect on all research indicators except homocysteine index. After 10 weeks of aerobic-resistance training, total cholesterol and HDL values showed a significant decrease and increase, respectively. However, in the resistance-aerobic group, only HDL values increased significantly. Insulin values were not significant before and after both experimental groups. Hemoglobin A1C values were significantly different only before and after aerobic-resistance training.
Conclusion: Aerobic-resistance training can improve insulin resistance by reducing fasting glucose and insulin levels.