Document Type : Research Paper
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Abstract
The aim of this Study was to investigate the Effects of 12 weeks Combined Training on Plasma Adiponectin and IL-6 in overweight females. 40 non athlete and overweight female students (BMI=25-30), were Selected and divided randomly into two Experimental and control groups, equally. Training program was done seven days a week for 12 weeks. The Endurance training Program, which was Performed four Sessions per week, Included Intermittent training. Two Sessions per week were assigned to Progressive Resistance training Consisted of circuit Trainings. One session per week was also allocated to handball training. Blood samples were taken in fasting state from all subjects. Plasma Adiponectin and IL-6 Concentrates were measured using ELISA method. The Statistical analysis was done by ANOVA with Repeated measure (2×2), at the Significance level of P
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1. Adamandia D, Kriketos A, Gan S K, Poyten A. Exercise increases adiponectin levels and insulin sensitivity in humans. Diabetes Care. 2004; 27(2): 629-30.
2. Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, Klarlund Pedersen B. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol. 2000; 529(1): 237-42.
3. Lambers S, Van Laethem C. Influence of combined exercise training on indices of obesity, diabetes and cardiovascular risk in type 2 diabetes patients. Clin Rehabil. 2008; 22(6): 483-92.
4. Poirier P, Giles T, Bray G, Hong Y, Stern J, Pi-Sunyer X. Obesity and cardiovascular disease: Pathophysiology, evaluation and effect of weight loss. Circulation. 2006; 113(6): 898-918.
5. Fenster C, Weinsier R, Darley-Usmar V, Patel R. Obesity, aerobic exercise, and vascular disease: The role of oxidant stress. Obes Res. 2002; 10(9): 964 –8.
6. Gideon R, Hajer T W, Haeften V, Frank L G, Visseren. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J. 2008; 29(24):2959-71.
7. Kelly A S, Steinberger J, Olson T P, Dengel D R. In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metabolism. 2007; 56(7): 1005-9.
8. Wajchenberg B L. Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome. Endocr Rev. 2000; 21(6): 697-738.
9. Zhuang X , Zhao M, Weng C, Sun N. Adipocytokines: A bridge connecting obesity and insulin resistance. Med Hypotheses. 2009; 73(6): 981–5.
10. Krista V, Surabhi B, Emily C, Shane P. Adipokine responses to acute resistance exercise in trained and untrained men. Med Sci Sports Exerc. 2010; 42(3): 456-62.
11. Lago R, Go´mez R, Go´mez J, Dieguez C. Adipokines as novel modulators of lipid metabolism. Trends Biochem Sci. 2009; 34(10): 33-8.
12. Chin M, Archie Y, Lo X, Mimi Y, Sham, Y. Obesity, diet, exercise and weight control - a current review. J Hong Kong Med Assoc. 1992; 44(3): 21-9.
13. Pedersen B, Febbraio M. Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev. 2008; 88(4): 1379-406.
14. Agha Alinejad H, Molanouri Shamsi M. Exercise induced release of Cytokines from skeletal muscle: Emphasis on IL-6. Iraninan Journal of Endocrinology and Metabolism. 2010; 12(2): 181-90.
15. Gleeson M. Immune function in sport and exercise. J Appl Physiol. 2007; 103:693-699.
16. Martin L J, Woo J G, Daniels S R, Goodman E, Dolan L M. The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity. J Clin Endocrinol Metab. 2005; 90(7): 4255-9.
17. Lago F, Go´mez R, Go´mez-Reino JJ, Gualillo O. Adipokines as novel modulators of lipid metabolism. Trends Biochem Sci. 2009; l (34): 10.
18. Jurimae J, Purge P, Jurimae T. Adiponectin is altered after maximal exercise in highly trained male rowers. Eur J Appl Physiol. 2005; 93(4): 502-5.
19. Punyadeera C, Zorenc A, Koopman R, McAinch A, Smit E, Manders R. The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle. Eur J Endocrinol. 2005; 152(3): 427-36.
20. Kern P A, Di Gregorio G B, Lu T, Rassouli N, Ranganathan G. Adiponectin expression from human adipose tissue: Relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes. 2003; 52(7): 1779-85.
21. Kraemer R, Aboudehen K, Carruth A, Durand R, Acevedo E, Hebert E, et al. Adiponectin responses to continuous and progressively intense intermittent exercise. Med Sci Sports Exerc. 2003; 35(8): 1320-5.
22. Ahmadizad S, Haghighi A, Hamedinia M. Effect of resistance versus endurance training on serum adponectin and insulin ressistance index. Eur J Endocrinol. 2009; 157(5): 625-31.
23. Mohebbi H, Talebi Gorgani E, Hedayati M, Fathi R. Effect of exercise training on high molecular weight adiponectin in healthy male rat. Iraninan Journal of Endocrinology and Metabolism. 2009; 11(3): 315-21. (In Persian)
24. Landers J. Maximums based on Reps. Natl. strength cond. As-soc. J. 1985; 1(6):60-61.
25. Helalizadeh M, Gaeini A A, Kordi M R, Ravasi A A, Hedayati M. The effects of 12 weeks combined training on plasma apelin and insulin resistance index in overweight females. Journal of Sport Biosciences 2015; 7(1): 93-108. (In Persian)
26. Lee D, Cheng R, Nguyen T, Fan T, Kariyawasam A P, Liu Y, et al. Characterization of apelin, the ligand for the APJ receptor. J Neurochem. 2000; 74(1): 34–41.
27. Li L, Yang G, Li Q, Tang Y, Yang M, Yang H, et al. Changes and relations of circulating visfatin, apelin, and resistin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects. Exp Clin Endocr Diab. 2006; 114(10): 544-8.
28.Szokodi I, Tavi P, Földes G, Voutilainen-Myllylä S, Ilves M, Tokola H, et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circ Res. 2002; 91(5): 434–40.
29. Tatemoto K, Hosoya M, Habata Y, Fujii R, Kakegawa T, Zou M X, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998; 251(2): 471–6.
30. Haghshenas R, Gilani N, Jafari M. Effect of 16 weeks endurance training and high fat diet on plasma level of interleukins-6, 10 and nesfatin-1 of rats. Sport Physiology. 2015; 24(6): 49-60. (In Persian)
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