Document Type : Research Paper
Authors
Professor in Sport Physiology Faculty of Physical Education and Sport Sciences Ferdowsi University of Mashhad
Abstract
The aim of this study was to investigate the effect of selected wrestling exercise with L-arginine supplementation on response of vascular endothelial growth factor (VEGF) and endostatin in elite wrestlers. In this practical and semi experimental study, 20 elite wrestlers (age: 21.13±2.47 years and BMI: 24.14±1.71 kg.m-2) were selected by convenience sampling method and they were randomly assigned into supplement (n=10) and placebo (n=10) groups. During the study, both groups were at the end of general preparatory phase and they are alike participated in a special wrestling training program and at the same time supplementation and placebo groups for 14 days were used daily 0.1 g.kg-1 respectively taking l-arginine and placebo. Serum levels of VEGF and endostatin levels of all subjects before and after the training period were measured by ELISA methods. Serum VEGF and endostatin levels (blood sample 3cc) were measured by ELISA methods, and the results were analyzed by SPSS at the significant level (P<0.05). There was a significant increase in the levels of VEGF and VEGF to endostatin ratio in supplementation group compared to placebo (P≤0.05). However, there was no significant change in the levels of endostatin (P≥0.05). It’s seems that specific wrestling training with L-arginine consuming together, could possibly cause more stimulation of the process of angiogenesis in wrestlers.
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