Document Type : Research Paper

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Abstract

Obesity is considered a growing cause of cardiovascular diseases. Intercellular adhesion molecules and cytokines associated with inflammation are new prognostic and diagnostic factors for cardiovascular disease. Accordingly, the present study attempted to investigate the effect of omega-3 consumption and participate in aerobic activity on sICAM-1 and cytokines associated with inflammation in obese elderly women. Accordingly in a Quasi-experimental, double-blinded study 40  obese women (BMI ≥30) 55 to 65 years were randomly and easily-accessible selected, and then were randomly categorized into 4 groups of 10 individuals- exercise- placebo, exercise - supplements, supplements and placebo. Individuals in the supplements group consumed 2080 mg omega-3 supplements for 8 weeks and placebo consumption group using dextrose 2%. Exercise program included aerobic exercise 45 to 60 percent of maximum heart  rate for 8 weeks, 60 minute and 3 sessions per week. After 12 h fasting in the pre-test and 48 hours after the last training session, blood sampling was obtained. Resulting data were analyzed by dependent t-tests, two-way ANOVA test and Tukey post hoc test was used at 5% alpha error level (p< 0.05). statistical test results indicated that there is a significant interactive effect between exercise and supplements in reducing serum sICAM-1 factor (P

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