Document Type : Research Paper
Authors
Abstract
The most of studies have been assessed caffeine prooxidant-antioxidant effects, introduced it as an antioxidant substance. However, some authors believed that caffeine has an oxidative effect. The aim of this study was to investigate the effects of 5 mg.kg-1 caffeine consumption during one Session incremental exercise on oxidative stress in active men. In order to, MDA as marker of lipid peroxidation and GPX and SOD as enzymatic antioxidants were measured in blood serum. therefore ten men students of physical education (age: 21.4± 1.6 years, BMI values: 23.31± 2.39 kg/m2, and Bruce protocol time (14.36 ± 1.58 min) voluntarily participated in this study. Bruce test was done in two sessions separately [interval between sessions were 5 days] and subjects participated in two conditions: placebo consumption in first session and 5mg.kg caffeine dosage in second session. Venous blood samples were obtained for analysis before exercise and 5 mg/kg caffeine dose / placebo ingestion (Pre) and immediately after the test (Post). Findings were analyzed by SPSS.18 and Excel 2003 soft wares. The result of this study indicated that 5 mg/kg caffeine consumption in comparison to placebo, decreased MDA and increased GPX significantly (P<0/05). But there was no significant difference between groups for SOD (P= 0/398). Generally it seems 5mg.kg-1 caffeine dosage inhibited exercise-induced oxidative stress in according to lipid peroxidation decrease and improves in antioxidant activities
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