Document Type : Research Paper
Authors
1 M.Sc. of Sport Physiology, Karaj PNU University
2 Associate Professor of Sport Physiology, Karaj PNU University
3 Professor of Sport Physiology, University of Isfahan
Abstract
The aim of this experimental research is to evaluate resistance training by up-to-the moment recording of mouse activities. Statistical population: Male mice (C57BL6-10 weeks old approximate weight 18-25 g) were randomly selected. The samples exercised in two groups: A (no light stimulus, 12 mice) B (with light stimulus, 15 mice) using a variable angle ladder with slope movement in 30°, 60° and 85°. The device consisted of four separate channels with a variable angle ladder at the bottom and movement sensors on each channel wall that recorded and drew the mathematical graph model of every training mouse activity separately using a particular hardware and software. Analyzing graphs showed that in the assumed exercise – training protocol members of one group in the same condition had not exercised similarly and their exercising model was significantly different by virtue of speed, time and intensity graphs. This difference was observed even in various training days of a mouse in comparison with itself. Therefore, the research indicated that it is impossible to assume the training activity of a group of mice in a resistance training to be the same even in a similar condition. As a result, the precise way of separating and grouping the trained mice is to monitor the training momently. With this method the effect of implemented training on each mouse is recorded and analyzed independently from others.
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- Kevin C, Kregel D L. Resource book for the design of animal exercise protocols; 2006. On February 7, 2006, the American Physiological Society (APS) published a Resource Book for the Design of Animal Exercise Protocols.
- Sacca R, Elder B. The C57BL/ 6 mouse. The role of the C57BL/6N mouse in the creation of future genetically engineered models. Charles River Laboratories International, Inc; 2013.
- Kondziella W. A new method for the measurment of muscle relaxation with mice. Archives Internationales de Pharmacodynamie et de Therapie. 1964; 152: 277-84.
- Sadeeka M. Resistance exercise training attenuates wasting of the extensor digitorum longus muscle in mice bearing the Colon-26 adenocarcinoma. School of Nursing, Virginia Commonwealth University; 2001. . Jan;2(3):155-66
- Suk H O Suk-Ho Lee, B.S., M.A,. Interacton of insulin like growth factor-1 and resistance training on skeletal muscle mass and function. The University of Texas at Austin; 2002.
- David J, Green B G. Mouse shoulder morphology responds to locomotor activity and the kinematic differences of climbing and running. Jurnal of Experimental Zoology. 2012; 318: 621–38.
- Karsten Kru ger1* DKG. Functional and muscular adaptations in an experimental model for isometric strength training in mice. PLoS ONE 8(11): e79069. https://doi.org/10.1371/journal.pone.0079069.
- Rockville P, Bethesda M. What types of animals are research? The American Physiological Society; 2013. 9650Rockville pike p. 20814-3991.
- Magalhaes J, Fraga M, Lumini-Oliveira J, Goncalves I, Costa M, Ferreira R, et al. Eccentric exercise transiently affects mice skeletal muscle mitochondrial function. Applied Physiology, Nutrition, and Metabolism=Physiologie Appliquee, Nutrition et Metabolisme. 2013; 38(4): 401-9.
- Chavanelle V, Sirvent P, Ennequin G, Caillaud K, Montaurier C, Morio B, et al. Comparison of oxygen consumption in rats during uphill (concentric) and downhill (eccentric) treadmill exercise tests. Journal of Sports Science & Medicine. 2014; 13(3): 689-94.
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