Document Type : Research Paper
Author
Associate Professor of Sport Physiology, Arak University
Abstract
Diabetes mellitus affect male reproductive function at multiple levels including control of spermatogenesis. The aim of this research was assessing the effect of aerobic training on reproductive parameters in diabetic male rats. Thirty male Wistar rats (age: 2-3 mount, weight: 200-250 gr) randomly divided in to three groups: healthy control, diabetic control and diabetic trained (n=10 each). A single intraperitoneal injection of streptozotocin at a dose of 55 mg/kg was used for induction of diabetes. One week after streptozotocin injection, the endurance training protocol was performed for eight weeks (five bouts per week of treadmill running each 20-60min with 27 m/min) and forty-eight hours after the last training session, left epididymis of the rats was examined for studying sperm parameters and blood serum samples were examined for evaluating reproductive hormones. Data were analyzed using one-way ANOVA and turkey’s post hoc test at 0.05%. All of the sperm parameters (count, motility, morphology and viability) significantly were lower in diabetic rat when compared with healthy control group (P<0.05), but, the data showed a significant elevation in all of the sperm parameters in diabetic + training when compared with diabetic control group (P<0.05). Also, the data showed a significant high in sex hormones (testosterone, luteinizing hormone, follicle-stimulating hormone) in diabetic + training when compared with diabetic control group (P<0.05). Exercise training can attenuate detrimental effects of diabetes mellitus on the sperm parameters and sex hormones in an experimental model.
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