Document Type : Review Article
Authors
1 M.Sc. Student of Sport Physiology, Shahid Cahmran University of Ahvaz
2 Associate Professor of Neurology, Jundishapur Medical Science University of Ahvaz
3 Assistant Professor of Sport Physiology, Shahid Chamran University of Ahvaz
4 Assistant Professor of Radiology, Jundishapur Medical Science University of Ahvaz*
Abstract
The purpose of this review is the systemic investigate of the effect of regular physical activity on some cytokines in people with multiple sclerosis. A systematic review was made based on MeSH system word on the databases of Pubmed, Googlescholar, Sciencedirect and Springer in English and the databases of Magiran and SID in Persian. The criteria included studies published in English and Persian, period 15 years, in people with multiple sclerosis, investigate effect of regular physical activity and assess anti-inflammatory and pro-inflammatory. Methodology assessed through PEDro scale. Between 1320 study that reviewed, 18 study that have the criteria selected. PEDro scale mean was 6.72±1.12. studies have used endurance (3 study), resistance (5 study), combine (6 study), vibration (a study) and aquatic training (3 study). In the studies reviewed, interleukin 6 and 10 were the most used (10 and 9 study, respectively). Although, further studies are needed, regular physical activity can consider an adjuvant therapy in multiple sclerosis disease, and through cytokine regulation affect multiple sclerosis disease process.
Keywords
Main Subjects
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2. Pak F, Nafariyeh T, Asghari N, Shokrollahy M, Kokhaei P. Immunopathology of multiple sclerosis. Koomesh. 2013;14(2):117-29. (In Persian).
3. Inglese M. Multiple sclerosis: New insights and trends. Am J Neuroradiol. 2006;27(5):954-7.
4. Ploeger HE, Takken T, De Greef MH, Timmons BW. The effects of acute and chronic exercise on inflammatory markers in children and adults with a chronic inflammatory disease: a systematic review. Exerc Immunol Rev. 2009;15(1): 6-41.
5. Moazzami M, Fathi M, Soltani M, Gelardi N. The effects of aerobic exercise in water on cortisol levels and tgf-β in patients with multiple sclerosis. Quarterly J Sabzevar Uni Med Sci. 2014;21(2):207-16. (In Persian).
6. Torabipour A, Asl ZA, Majdinasab N, Ghasemzadeh R, Tabesh H, Arab M. A study on the direct and indirect costs of multiple sclerosis based on expanded disability status scale score in Khuzestan, Iran. Inter J Preven Med. 2014;5(9):1131-8.
7. Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, et al. Defining the clinical course of multiple sclerosis the 2013 revisions. Neurol. 2014;83(3):278-86.
8. Plantone D, de Angelis F, Doshi A, Chataway J. Secondary progressive multiple sclerosis: Definition and measurement. CNS Drugs. 2016;30(6):517-26.
9. Alexander WS. Suppressors of cytokine signalling (SOCS) in the immune system. Nat Rev Immunol. 2002;2(6):410-6.
10. Scholz C, Patton KT, Anderson DE, Freeman GJ, Hafler DA. Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation. Immunol. 1998;160(3):1532-8.
11. Turner AP, Kivlahan DR, Haselkorn JK. Exercise and quality of life among people with multiple sclerosis: looking beyond physical functioning to mental health and participation in life. Archives of physical medicine and rehabilitation. 2009;90(3):420-8.
12. Sospedra M, Martin R. Immunology of multiple sclerosis. Annu Rev Immunol. 2005; 23: 683-747.
13. Cannella B, Raine CS. Multiple sclerosis: Cytokine receptors on oligodendrocytes predict innate regulation. Ann Neurol. 2004;55(1):46-57.
14. Mahon BD, Gordon SA, Cruz J, Cosman F, Cantorna MT. Cytokine profile in patients with multiple sclerosis following vitamin D supplementation. Neuroimmunol. 2003;134(1):128-32.
15. Lovett-Racke AE, Rocchini AE, Choy J, Northrop SC, Hussain RZ, Ratts RB, et al. Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes. Immunity. 2004;21(5):719-31.
16. Majdinasab N, Behbahani MH, Galehdari H, Mohaghegh M. Association of interleukin 7 receptor gene polymorphism rs6897932 with multiple sclerosis patients in Khuzestan. Iran J Neurol. 2014;13(3):168-71.
1. 17. Dembic Z. The cytokines of the immune system: The role of cytokines in disease related to immune response. Miniapoles: Academic Press; 2015. P.10-65.
17. Ranjbar R, Ahmadizad S, Khoshniyat-Niko M, Mohsenzade A. The effect of endurance training accompanied by fasting and a period of detraining on serum leptin and fructosamine in overweight men. Iran J Endocrinol Metabol. 2013;15(3):269-78. (In Persian).
18. Abolfathi F, Ranjbar R, Shakerian S, Yazdanpanah L. The effect of eight weeks aerobic interval training on adiponectin serum levels, lipid profile and hs-crp in women with type ii diabetes. Iran J Endocrinol Metabol. 2015; 7(4): 316-25. (In Persian).
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20. Maghsogi N, Khosravi N, Ravasi AA. The effect of selective training (aerobic and strength) on some cytokine in male and female patient with MS. J Sport Biol. 2011;10(3):5-23. (In Persian).
21. Pouretezad M, Babadi M, Soiuki HN, Nasab NM. A comparison of two exercise therapy programs on functional balance in people with multiple sclerosis. Jentashapir J Health Res. 2011;3(1):283-91. (In Persian).
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24. Maltseva DV, Sakharov DA, Tonevitsky EA, Northoff H, Tonevitsky AG. Killer cell immunoglobulin-like receptors and exercise. Exerc Immunol Rev. 2011;17(1):150-63.
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