اثر دو الگوی تمرین با نسبت روزهای استراحت به تمرین متفاوت و مصرف مکمل عسل طبیعی بر غلظت اینترلوکین-6 سرم و بیان آن در بافت هیپوکمپ موش‌های صحرایی نر نابالغ

نوع مقاله : مقاله پژوهشی

نویسندگان
احمد رحمانی 1
علی گرزی 2
زهرا محمدی 3
1 استادیار رفتار حرکتی، دانشگاه زنجان، زنجان، ایران
2 دانشیار فیزیولوژی ورزشی، دانشگاه زنجان، زنجان، ایران
3 کارشناسی‌ارشد فیزیولوژی ورزشی کاربردی، دانشگاه زنجان، زنجان، ایران
10.22089/spj.2019.3748.1505
چکیده
هدف از انجام پژوهش حاضر، بررسی تأثیر دو الگوی تمرین با نسبت روزهای استراحت به تمرین متفاوت همراه با مصرف عسل طبیعی، بر میزانIL-6  سرم و بیان آن در بافت هیپوکمپ بود. 36 موش صحرایی نر نابالغ در شش گروه کنترل، عسل (10 درصد در آب آشامیدنی)، تمرین تناوبی شدید چهارروزه، تمرین تناوبی شدید چهارروزه + عسل، تمرین تناوبی شدید هفت‌روزه و تمرین تناوبی شدید هفت‌روزه + عسل قرار گرفتند. دوره‌های تمرین چهارروزه (سه روز تمرین و یک روز استراحت) و هفت‌روزه (شش روز تمرین، یک روز استراحت) تناوبی شدید (16-10 متر در دقیقه در هفتة اول و 40-36 متر در دقیقه در هفتة آخر) به‌مدت یک ماه انجام شد. غلظت IL-6 سرم در گروه تمرین هفت‌روزه نسبت به گروه کنترل بالاتر بود (P = 0.001). سطوح IL-6 سرم در گروه عسل- تمرین هفت‌روزه پایین‌تر از گروه تمرین هفت‌روزه بدون مکمل (P = 0.018) بود. بین گروه چهارروزه و گروه کنترل تفاوت معناداری وجود نداشت (P = 0.946). هر دو نوع تمرین‌های هفت‌روزه (P = 0.007) و چهارروزه (P = 0.005) موجب بالاتررفتن معنادار بیان ژن IL-6 هیپوکمپ شدند؛ اما مصرف مکمل عسل در گروه هفت‌روزه (P = 0.583) و چهارروزه (P = 0.983) موجب تعدیل بیان ژن IL-6 هیپوکمپ نشد؛ بنابراین، تمرین‌های تناوبی شدید بیان ژن IL-6 را در هیپوکمپ افزایش می‌دهند؛ اما دوره‌های تمرینی طولانی‌تر موجب افزایش سیستمیک سایتوکاین‌های التهابی می‌شوند. مصرف عسل اثرهای مرکزی تمرین‌های تناوبی شدید را تعدیل نمی‌کند؛ بااین‌حال، می‌تواند التهاب سیستمیک را کاهش دهد. همچنین، اثرهای ضدالتهابی عسل در شرایط غیرتمرینی و غیرالتهابی، مشاهده نمی‌شوند.
کلیدواژه‌ها
تمرین تناوبی شدید
عسل
اینترلوکین-6
هیپوکمپ

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فیزیولوژی ورزشی
دوره 11، شماره 42 - شماره پیاپی 42
تابستان 1398
مرداد 1398
صفحه 113-132

  • تاریخ دریافت 14 آبان 1397
  • تاریخ بازنگری 20 خرداد 1398
  • تاریخ پذیرش 27 خرداد 1398