نوع مقاله : مقاله مروری

نویسندگان

1 دانشجوی کارشناسی‌ارشد فیزیولوژی ورزشی، دانشگاه شهرکرد، گروه علوم ورزشی

2 استادیار فیزیولوژی ورزشی، دانشگاه شهرکرد، گروه علوم ورزشی

3 استاد فیزیولوژی ورزشی، دانشگاه اصفهان، گروه علوم ورزشی

چکیده

پژوهش‌های زیادی تأثیر فعالیت ورزشی هوازی مزمن را بر عوامل مرتبط با بیماری کبد چرب غیر الکلی بررسی کرده‌اند هدف از این پژوهش تعیین و بررسی تأثیر شدت‌های متفاوت تمرینات ورزشی هوازی مزمن (کم، متوسط و بالا) بر آلانین آمینوترانسفراز ، آسپارتات آمینوترانسفراز، آلکالین فسفاتاز و گاما گلوتامین ترانسفراز در مردان و زنان سنین مختلف بود که به صورت یک مطالعه مرور نظام‌مند و فراتحلیل در سال ۱۳۹۹ انجام شد. پایگاه‌های اطلاعاتی، ScienceDirect،PubMed، Scopus و Google Scholar همراه با کلمات کلیدی جستجو شد. تعداد ۱۲۰ مقاله غیر مروری و با کیفیت مناسب تمرین هوازی بررسی قرار گرفتند و ۲۲ مقاله معیار ورود فراتحلیل را کسب کردند . بر این اساس ۱۵۶۰ نفر با میانگین ۱۰ ± ۵۲ سال بود. دارای بیماری کبد چرب مورد بررسی قرار گرفتند. اثرات مداخله با استفاده از SMD و مدل اثرات تصادفی ارزیابی گردید. در بررسی نتایج متاآنالایز تمرین هوازی در کل با هر شدتی باعث کاهش معنی‌دار سطوح آسپارتات آمینوترانسفراز، آلکالین فسفاتاز و گاما گلوتامین ترانسفراز می‌گردد. سطوح آلانین آمینوترانسفراز در تمرینات با شدت بالا کاهش بیشتری نسبت به تمرینات با شدت متوسط (P= 0.01)دارد. سطوح آسپارتات آمینوترانسفراز در تمرینات با شدت متوسط(P= 0.001) کاهش بیشتری نسبت به تمرینات با شدت بالا (P= 0.03)دارد. تأثیر تمرینات با شدت بالا و شدت متوسط بر سطوح آنزیم گاما گلوتامین ترانسفراز معنی‌دار نبود (P= 0.2 ) .یافته ها نشان می دهد که تمرین‌های هوازی با شدت بالا، متوسط و کم موجب کاهش آنزیم‌ها شاخص کبد چرب در بیماران کبد چرب غیر الکلی می‌گردد.

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