آثار یک دوره تمرین هوازی و مصرف خوراکی استویا بر شاخص‌های گلیسمیک، مقاومت به انسولین و عملکرد سلول‌های بتای موش‌های صحرایی دیابتی

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران

2 دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه رازی، کرمانشاه، ایران

چکیده
هدف از اجرای این پژوهش، بررسی اثر تمرین هوازی و مصرف عصارة استویا بر شاخص‌های گلیسمیک، مقاومت به انسولین و عملکرد سلول‌های بتای موش‌های صحرایی دیابتی بود. در این مطالعه، 28 ﺳﺮ موش صحرایی ﻧﺮ ﻧﮋاد وﻳﺴﺘﺎر ﺑﺎ میانگین وزنی 8/15± 86/188 ﮔﺮم به‌ﻃﻮر ﺗﺼﺎدﻓﻲ به چهار گروه (ﻛﻨﺘﺮل دﻳﺎﺑﺘﻲ، دﻳﺎﺑﺘﻲ ﺗﻤﺮﻳﻦ، دیابتی عصاره و دیابتی تمرین همراه با مصرف استویا) تقسیم شدند. ﺗﻤﺮﻳنات هوازی ﺷﺎﻣﻞ دویدن روی نوار گردان، پنج روز در ﻫﻔﺘﻪ به‌مدت شش ﻫﻔﺘﻪ بود و دریافت عصاره نیز برای همین مدت ادامه یافت. در پایان مداخلة ﺳﻄﻮح ﮔﻠﻮﻛﺰ، اﻧﺴﻮﻟﻴﻦ سرم برای سنجش شاخصHOMA-IR  و HOMA-β اﻧﺪازه‌ﮔﻴﺮی شد. نتایج نشان داد که برنامة تمرینی هوازی و دریافت عصارة استویا سبب کاهش معنادار سطوح گلوکز و افزایش معنادار HOMA-β درگروه‌های تجربی نسبت به گروه کنترل دیابتی شد (0.05P <). سطوح مقاومت به انسولین، در گروه‌های تجربی پایین‌تر از گروه دیابتی بود؛ اما این تفاوت به‌لحاظ آماری معنادار نبود(P >0.05)؛ بنابراین، می‌توان نتیجه گرفت ﮐﻪ تمرین هوازی و ﻣﺼﺮف ﻋﺼﺎرة استویا، هرکدام ﺑﻪ‌ﺗﻨﻬﺎﯾﯽ و ترکیبی می‌توانند ﺑﻪ ﺑﻬﺒﻮد ﻣﻌﻨادار گلوکز و ﻋﻤﻠﮑﺮد ﺳﻠﻮل‌ﻫﺎی ﺑﺘﺎی ﭘﺎﻧﮑﺮاس موش‌ﻫﺎی صحرایی دﯾﺎﺑﺘﯽ منجر شوند. افزون‌براین، ﻣﺼﺮف عصاره ﻫﻤﺮاه ﺑﺎ ﺗﻤﺮﯾﻦ در ﻣﻘﺎﯾﺴﻪ ﺑﺎ ﻣﺼﺮف عصارة استویا و تمرین هوازی، ﺑﻪ‌ﺗﻨﻬﺎیی می‌توانند تأثیر مضاعفی داشته باشند.

کلیدواژه‌ها

موضوعات

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فیزیولوژی ورزشی
دوره 10، شماره 39
پاییز 1397
آبان 1397
صفحه 127-142

  • تاریخ دریافت 06 دی 1396
  • تاریخ بازنگری 04 اردیبهشت 1397
  • تاریخ پذیرش 15 اردیبهشت 1397