نوع مقاله : مقاله پژوهشی

نویسندگان

استادیار گروه علوم ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه اردکان، اردکان، ایران.

چکیده

اهداف:امروزه الگوی تمرینی مناسب همراه با مصرف گیاهان دارویی نقش مهمی در تنظیم تعادل انرژی، کاهش شاخص‌های التهابی و افزایش دفاع ضداکسایشی در افراد سالمند چاق دارد. لذا هدف پژوهش حاضر بررسی تاثیر 8 هفته تمرین تناوبی شدید و مصرف چای سبز بر سطوح سرمی تیوردوکسین رودوکتاز-1،پاراکسوناز-1، اینترلوکین یک بتا،اینترلوکین شش و گالانین در مردان چاق سالمند تمرین نکرده، بود.
مواد و روش‌‌ها:در این مطالعه ۴۸ مرد سالمند چاق تمرین‌نکرده به طور تصادفی در چهار گروه شامل تمرین تناوبی شدید، تمرین تناوبی شدید همراه با مصرف چای سبز، مصرف چای سبز و کنترل قرار گرفتند. پروتکل تمرین به مدت 8 هفته، هفته‌ای 3 جلسه و با شدت 90% ضربان قلب ذخیره اجرا شد.چای سبز روزانه به مقدار۴۵۰ میلی‌گرم(شش کپسول در روز)دریافت ‌شد. نمونه‌های خونی قبل و 48 ساعت پس از آخرین جلسه تمرینی گرفته شد. داده‌ها با استفاده از آزمون شاپیرو-ویلک و تحلیل کوواریانس دوراهه از طریق نرم افزار SPSS-26 تجزیه و تحلیل شدند.
یافته‌ها:نتایج نشان داد که اثر ترکیبی تمرین همراه با مصرف چای سبز و همچنین اثر تمرین به تنهایی باعث افزایش معنی‌دار سطوح تیوردوکسین رودوکتاز-1،پاراکسوناز-1 و کاهش معنی‌دار سطوح اینترلوکین یک بتا،اینترلوکین شش و گالانین شدند(P<0.05)؛ولی مصرف چای سبز به تنهایی تغییرات معنی‌دار را نشان نداد(P>0.05).بیشترین درصد تغییرات (افزایش و کاهش) ایجاد شده در متغیرهای بیوشیمیایی به گروه تمرین همراه با مصرف چای سبز اختصاص داشت.
نتیجه‌گیری: انجام تمرین تناوبی شدید همراه با مصرف چای سبز، بیشترین تأثیر را بر افزایش سطوح آنزیم‌های آنتی‌اکسیدانی، کاهش نشان‌گرهای التهابی و تعادل انرژی در مردان سالمند چاق تمرین‌نکرده داشت.

کلیدواژه‌ها

موضوعات

  1. Liberale L, Montecucco F, Tardif JC, Libby P, Camici GG. Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease. European Heart Journal. 2020;41(31):2974-82.
  2. Nunan E, Wright CL, Semola OA, Subramanian M, Balasubramanian P, Lovern PC, Fancher IS, Butcher JT. Obesity as a premature aging phenotype—implications for sarcopenic obesity. GeroScience. 2022;44(3):1393-405.
  3. Mokra D, Joskova M, Mokry J. Therapeutic effects of green tea polyphenol (‒)-epigallocatechin-3-gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and apoptosis. International Journal of Molecular Sciences. 2023;24(1):340.
  4. Nobari H, Saedmocheshi S, Chung LH, Suzuki K, Maynar-Mariño M, Pérez-Gómez J. (2021). An overview on how exercise with green tea consumption can prevent the production of reactive oxygen species and improve sports performance. International Journal of Environmental Research and Public Health, 2021;19(1):218.
  5. Arabzadeh E, Norouzi Kamareh M, Ramirez‐Campillo R, Mirnejad R, Masti Y, Shirvani H. Twelve weeks of treadmill exercise training with green tea extract reduces myocardial oxidative stress and alleviates cardiomyocyte apoptosis in aging rat: the emerging role of BNIP3 and HIF‐1α/IGFBP3 pathway. Journal of Food Biochemistry. 2022;46(12):e14397.
  6. Streb AR, Braga PGS, de Melo RF, Botelho LJ, Maranhão RC, Del Duca GF. Effects of combined physical exercise on plasma lipid variables, paraoxonase 1 activity, and inflammation parameters in adults with obesity: a randomized clinical trial. Journal of endocrinological Investigation. 2022;45(10):1991–7.
  7. Posnakidis G, Aphamis G, Giannaki CD, Mougios V, Aristotelous P, Samoutis G, Bogdanis GC. High-intensity functional training improves cardiorespiratory fitness and neuromuscular performance without inflammation or muscle damage. Journal of Strength and Conditioning Research. 2022;36(3):615-23.
  8. Herasymchuk U, Kravchun PG, Kadykova O. Galanin levels in hypertensive patients with obesity. Wiad Lek. 2022;75(1):79-84.
  9. Sun J, She Y, Fang P, Gu X, Zhang Z. Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2022;27(4):1415-25.
  10. Hooshmand Moghadam B, Rashidlamir A, Attarzadeh Hosseini SR, Gaeini AA, Kaviani M. The effects of saffron (crocus sativus L.) In conjunction with concurrent training on body composition, glycemic status, and inflammatory markers in obese men with type 2 diabetes mellitus: a randomized double‐blind clinical trial. British Journal of Clinical Pharmacology. 2022;88(7):3256-3271.
  11. Ghasemnian A, Sojasi F, Karimiasl Akram A, Norouzi H. Effects of 8 week strenuous endurance and high intensity interval training on thioredoxin reductase-1 enzyme and malondialdehyde in lung tissue of male wistar rats. Journal of Nurse and Physician within War. 2022;9(33):26-36
  12. Duan W, Zeng D, Huang J, Gu J, Li S, Zhou W, et al. Effect of modified total body recumbent stepper training on exercise capacity and thioredoxin in COPD: a randomized clinical trial. Scientific Reports. 2022;12(1):11139.
  13. Naderifar H, Mohammad khani Gangeh M, Mehri F, Shamloo Kazemi S. Effects of high intensity interval training and consumption of matcha green tea on malondialdehyde and glutathione peroxidase levels in women. Journal of Mazandaran University of Medical Sciences. 2022;32(212):42-53.
  14. Salimi Avansar M, Zar A. Comparing the effect of endurance and high intensity interval trainings on levels of Chemerin and protein of c-reactive plasma in obese children. Journal of Arak University of Medical Sciences. 2017;20(2):54-66.
  15. Karvinen S, Silvennoinen M, Vainio P, Sistonen L, Koch LG, Britton SL, et al. Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. Experimental Gerontology. 2016;79:46-54.
  16. Kline CJ, Porcari JP, Hintermeister R, Freedson PS, Ward A, McCarron RF, et al. Estimation of from a one-mile track walk, gender, age and body weight. Med. Sports Exerc. 1987;19:253-9.
  17. Kazemi A, Behpour N, Hematfar A. Effect of 12 weeks of green tea extract consumption on total antioxidant capacity (TAC), malondialdehyde (MDA) levels and superoxide dismutase, glutathione peroxidase and catalase activity of old rats' heart tissue in response to a bout acute exhaustive exercise. YAFTEH. 2020;22(2): 177-187.
  18. Shahidi F, Shakeri C, Delfani Z. The effect of eight weeks interval aerobic exercise and consumption of green tea supplementation on oxidative stress indices of inactive young girls. Razi Journal of Medical Sciences. 2019;25(11):72-84.
  19. Jówko E, Długołęcka B, Makaruk B, Cieśliński I. The effect of green tea extract supplementation on exercise-induced oxidative stress parameters in male sprinters. European Journal of Nutrition. 2015;54(5): 783-791.
  20. Marvi-Esfahani M, Alizade S. The effect of green tea supplement on some metabolic indicators and body composition after eight weeks of moderate intensity rhythmic aerobic exercise in obese women. Medical Journal of Mashhad University of Medical Sciences. 2021;64(2):2999-3013.
  21. Hellsten Y, Apple FS, Sjödin B. Effect of sprint cycle training on activities of antioxidant enzymes in human skeletal muscle. Journal of Applied Physiology. 1996;81(4): 1484-1487.
  22. Velayutham P, Babu A, Liu D. Green tea catechins and cardiovascular health: an update. Current Medicinal Chemistry. 2008;15(18):1840-1850.
  23. Frei B, Higdon JV. Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. The Journal of Nutrition. 2003;133(10):3275S-3284S.
  24. Ghasemi E, Afzalpour ME, Nayebifar S. Combined high-intensity interval training and green tea supplementation enhance metabolic and antioxidant status in response to acute exercise in overweight women. The Journal of Physiological Sciences. 2020;70(1):1-9.
  25. Rojano-Ortega D. Regular, but not acute, green tea supplementation increases total antioxidant status and reduces exercise-induced oxidative stress: a systematic review. Nutrition Research. 2021;94:34-43.
  26. Bagheri R, Rashidlamir A, Ashtary-Larky D, Wong A, Grubbs B, Motevalli MS, et al. Effects of green tea extract supplementation and endurance training on irisin, pro-inflammatory cytokines, and adiponectin concentrations in overweight middle-aged men. European Journal of Applied Physiology. 2020;120(4):915-923.
  27. Steckling FM, Farinha JB, Santos DL, Bresciani G, Mortari JA, Stefanello ST, et al. High Intensity interval training reduces the levels of serum inflammatory cytokine on women with metabolic syndrome. Experimental And Clinical Endocrinology & Diabetes. 2016; 124(10): 597-601.
  28. Ihalainen JK, Hackney AC, Taipale RS. Changes in inflammation markers after a 10-week high-intensity combined strength and endurance training block in women: the effect of hormonal contraceptive use. Journal Of Science and Medicine in Sport. 2019; 22(9):1044-1048.
  29. Banitalebi E, Razavi T, Norian M, Bagheri L. The effect of combined aerobic exercise training and green tea extract on serum TNF-α and IL-6 levels in obese women with type 2 diabetes. Daneshvar Medicine. 2016; 23(123):11-20.
  30. Basu A, Du M, Sanchez K, Leyva MJ, Betts NM, Blevins S, et al. Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome. Nutrition. 2011; 27(2):206-213.
  31. Ryu OH, Lee J, Lee KW, Kim HY, Seo JA, Kim SG, et al. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Research and Clinical Practice. 2006;71(3):356-358.
  32. Fathie M, Khairabadi S, Dehbashi M, Ketabdar B. Effect of green tea supplementation and eight weeks of aerobic exercise on serum galanin and lipid profile in untrained obese women. Iranian Journal of Nutrition Sciences & Food Technology. 2016; 10(4):33-40.
  33. Babaei Bonab S. The Effect of 12 Weeks of HIIT training and curcumin consumption on leptin and galanin levels in obese women. J Ardabil Univ Med Sci. 2020;20 (2):188-199.
  34. Yun R, Dourmashkin JT, Hill J, Gayles EC, Fried SK, Leibowitz SF. PVN galanin increases fat storage and promotes obesity by causing muscle to utilize carbohydrate more than fat. Peptides. 2005;26(11):2265-73.
  35. Muenzner M, Tappenbeck N, Gembardt F, Rülke R, Furkert J, Melzig MF, Siems WE, Brockmann GA, Walther T. Green tea reduces body fat via upregulation of neprilysin. International Journal of Obesity. 2016; 40(12):1850-1855.